Are you familiar with benign tumors?
A benign disorder is a non-cancerous growth in the body. Benign tumors differ from cancerous tumors in that they do not spread to other parts of the body. Benigns comprise cell mass that cannot metastasize or invade neighboring tissue.
Upon removal, these tumors don’t grow back. They are typically covered by an outer surface or enclosed within the epithelium. Benign tumors show slow progression and growth rate than malignant tumors. Common examples of benign tumors are moles and uterine fibroids.
Are benign tumors harmful?
They, although they will not locally invade the tissue still, some of its types can produce a negative impact on health. The progression of tumors may produce a mass effect that can compress tissue and cause nerve damage. They reduce blood flow to an area of the body, causing tissue death and organ damage. Tumors within an enclosed space, such as the respiratory tract, skull, sinus, or inside bones, negatively impact an individual’s health status. Benign brain tumors can be life-threatening but may not be life-threatening if they occur anywhere else in the body except the brain.
Mechanism of benign tumors:
1. Benign vs. Malignant:
Benign and malignant tumors differ in their pattern of invasiveness and progression. Non-invasive tumors are termed benign and invasive tumors are termed malignant tumors. Benign and malignant tumors differ in the pattern of progression also. They show slow growth, whereas malignant tumors are fast-growing tumors. Although benigns are not life-threatening compared to malignant tumours, both types can create life-threatening conditions in certain situations. Both tumors share general characteristics that often overlap.For example, doctors observe that benign tumors are highly differentiated, while malignant tumors are mostly undifferentiated; however, they also identify undifferentiated benigns and differentiated malignant tumors. The same applies to growth; although doctors typically note that these tumors grow slowly, researchers have also documented fast-growing cell growth.
2. Multistage carcinogenesis:
Carcinogenesis is the process in which cellular alteration leads to cancer. Tumors are developed by carcinogenesis. In multistage carcinogenesis, sequential epigenetic or genetic changes to a cell’s DNA exist, and each step gives rise to more advanced tumors. Multistage carcinogenesis is further broken into three main classes
- Initiation: It’s the initial stage where genetic mutation starts in a cell
- Promotion: It is associated with transformed cells’ clonal or repeated division.
- Progression: Progression is the stage when there is more genetic mutation occurring in tumor cells.
As mentioned earlier, the most common and prominent example is a tubular adenoma, in which tumor cells frequently progress to cancer.
Types of benign tumors:
. There are different types of benign tumors.
Adenomas:
Benigns that develop in organs and glands are termed benign tumors. The most common one is a polyp found in the colon. The probability of such tumors progressing towards malignant is less than 1 out of 10 that can be removed with surgery if necessary.
Fibroids
Benigns that are most commonly found in tumors are termed fibroids. Most of them are asymptomatic. Fibroids may become extremely painful if they grow into the uterus tissue. Such conditions required surgical removal to manage the pain.
Nevi tumors
Most people know them as moles that can appear anywhere on the body and grow in the skin. Nevi tumors vary in shape, size, and color. The most common colors are brown, tan, pink, or black. Consult your doctor if a mole changes color or size or shows progression or spread. It may be an indication of skin cancer and require surgical removal.
Osteochondromas
They are the most common types of non-cancerous bone tumors in young adults and children. It occurs when there is an overgrowth of cartilage and bone. Mostly they are painless and don’t require any treatment until and unless they become painful and need a problematic condition.
Papillomas
These tumors project in finger-like fronds and grow from epithelium tissue. They can be benign or malignant. Papilllomas can grow in the skin, cervix, breast ducts, or conjunctiva. Direct contact with an infection such as human papillomavirus (HPV) can cause these tumors.
Hemangiomas
These tumors occur due to inappropriate accumulation of blood vessel cells in the skin or internal organs. They are the most common type of birthmarks in the head, neck, and trunk. If they cause problems with vision, hearing, or eating, they require treatment with corticosteroids or other medication.
Causes of benign tumors:
The exact cause of benigns are still unknown. Its pathophysiology seems to link with certain factors, such as
- Environmental toxins such as radiation
- Genetic mutation
- Infection or inflammation
- Local injury or trauma
- Stress
- Diet
Benign Tumors’ Symptoms:
Benigns are commonly asymptomatic. Almost all types of tumors, either benign or malignant, are asymptomatic. Symptoms also depend on the type of tumor as well as its location. Generally, the symptoms of benign tumors are as follows.
- Chills
- Weight loss
- Loss of appetite
- Night sweats
- Pain or discomfort
- Fatigue
Based on locations, possible symptoms of benign brain tumors are
- Headaches
- Blurred vision
- Fuzzy memory
Diagnosis :
A variety of techniques can diagnose benign tumors. The key factor in diagnosis involves doctors determining whether the tumor is benign or malignant, which they can evaluate only through laboratory testing. Imaging tests can determine and locate the presence of benign tumors, including.
- CT scans
- MRI scans
- X-ray
- Ultrasounds
- Mammograms
The blood test is also used in diagnosis to determine cancer markers. A doctor performs a tumor biopsy to determine if the tumor is benign or malignant. A biopsy may be less invasive depending on the tumor’s location.
Treatment:
Small and asymptomatic benign tumors don’t need treatment until and unless they grow in size or cause major health problems such as pain or impairment in normal physiological functions. Initially, the doctor takes a wait-and-watch approach. If the doctor feels the requirement of treatment, it will depend on the tumor’s location. Tumor surgery is commonly performed by using a variety of endoscopic techniques that involve surgical incisions. Recovery time depends upon the invasiveness of the surgical procedure Incase of unsuccessful tumor removal by surgery. The doctor may proceed with the treatment with radiation. Radiation therapy helps reduce the size of tumors and prevent them from growing larger.
Bottom Line:
Benign tumors are non-cancerous growths with an unknown pathophysiology. They are usually noninvasive and show slow growth compared to malignant tumors, but in some cases, they may become malignant or life-threatening. Asymptomatic tumors require laboratory testing to diagnose them. Healthcare providers typically do not require treatment for them, but in cases of serious health problems, they may remove them surgically or with radiation therapy.
Author
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